We re-engineer macromolecules found in nature to create new medicines, materials and catalysts. Our research involves a mix of organic chemistry, synthetic biology and protein engineering.
We are based in the School of Chemistry at the University of Sydney. We collaborate widely with research groups locally and internationally. Our group is also part of the Sydney Nano Institute and the Drug Discovery Initiative.
Two primary areas of research in the lab currently are:
1. Cyclic/stapled peptides as therapeutic candidates that target protein-protein interactions involved in cancer
2. Encapsulin nanocompartments as synthetic organelles and molecular cages for controlling chemical and enzymatic catalysis
Feel free to contact Yu Heng to learn more!
At the School of Chemistry, we have established a bio-nano space for doing cross-disciplinary chemical science. This space, which we like to call The Incubator, houses the capacity to conduct synthesis, molecular biology, bacterial culture, protein production and biophysical analysis.
The Incubator is a collaboration between the Lau group and the DNA group of Dr Shelley Wickham.
Our equipment facilites include an AKTA Pure FPLC protein purification system, HPLC-SEC-MALS for protein characterisation, ChemiDoc system incl. fluorescence/NIR imaging, Olympus IX-81 inverted microscope, PCR machines, autoclave, centrifuges, incubators and shakers.
Check out our new photos of the Incubator lab space =)